Associate Professor Dr
Hoang Anh Hoang
Ho Chi Minh City University of Technology, HCMC, Vietnam
Title: Understanding phage–pathogen–fish interactions through wet-lab, immunological and -omics approaches
Hoang A. Hoang*,1,2, Trong-Tuong Ho1,2, Le P. Nga1,2, Tu Q. Vinh1,2, Dang T.H. Oanh3,
BA Diep4, Andrew Millard5, Nguyen T. Trung6
1Faculty of Chemical Engineering, Ho Chi Minh City University of Technology, HCMC, Vietnam
2Vietnam National University Ho Chi Minh City, Thu Duc District, HCMC, Vietnam
3College of Aquaculture and Fisheries, Can Tho University, Can Tho, Vietnam
4Department of Medicine, University of California, San Francisco, CA, USA
5Department of Genetics and Genome Biology, University of Leicester, Uni. Road, Leicester, UK
6Institut Européen de Chimie et Biologie, U1212 Inserm, Université de Bordeaux, France
*E-mail: hoang.a.hoang@hcmut.edu.vn
Antibiotics have long served as the primary means of preventing and treating bacterial diseases in humans, animals, and agricultural production systems. In food-producing animals and crops, their widespread use has contributed to substantial selective pressure, accelerating the development of antimicrobial resistance (AMR). AMR is a naturally occurring adaptive strategy through which microorganisms evolve resistance to antimicrobial compounds, and worrying resistance trends have been documented in Vietnamese aquaculture, where high antibiotic-resistant rates have been reported among pathogenic bacteria in fish farms. Bacteriophages (phages), viruses that specifically infect bacteria, have emerged as a promising alternative to antibiotics. Over the past four decades, the application of lytic phages in aquaculture has gained increasing attention, especially in response to the rapid rise of antibiotic-resistant pathogens.
In this presentation, we introduce the first study exploring multi-level interactions between phages, pathogens, and host immunity in striped catfish (Pangasianodon hypophthalmus), a key aquaculture species in Vietnam. Specifically, we investigate (i) phage–bacterial pathogen interaction, (ii) phage interactions on the fish innate immune response, and (iii) phage influences on the intestinal bacterial community. This integrative approach advances our understanding of phage biology in aquaculture and provides insights supporting phage-based strategies for disease control in fish production.
Keywords: phage, striped catfish, bacterial pathogens, innate immune response, genomics, metagenomics.
Biography of the presenting author
Hoang completed his PhD at the Tokyo Institute of Technology, Japan, in 2014. He currently leads the bacteriophage research group at Ho Chi Minh City University of Technology, Vietnam. His research focuses on phage biology, antimicrobial resistance, and phage-based disease control in agriculture. Dr. Hoang has published extensively in reputable international journals and has served as Principal Investigator for 14 research projects.
Presenting author details
Full name: Hoang Anh Hoang
Contact number: +84-906318412
Email: hoang.a.hoang@hcmut.edu.vn
Website: https://hoanglab.vn/
Session name/ number: Agricultural Biotechnology
Category: Oral presentation